Crystal forms of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide
US8466173B2 · kind B2 · utility
4Cited by
3References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 6, 2010 |
| Grant date | Jun 18, 2013 |
| Priority date | — |
| Expiry date | Feb 15, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Crystalline polymorphs of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.