Patent · US Active

SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors

US8466286B2 · kind B2 · utility

627Cited by

55References

13Claims

0Family size

Assignee

Cercacor Laboratories, Inc. · US

Inventors

Emile Bellott · Beverly, US
Dongsheng Bu · Piscataway, US
James J. Childs · Bolton, US
Christopher R. Lambert · Hudson, US
Hubert A. Nienaber · Worcester, US
Shirley J. Shi · Lexington, US
Zhaolin Wang · Wellesley, US
Jerome J. Workman, Jr. · Appleton, US
Alex Zelenchuk · Stoughton, US

Key dates

Filing date	Aug 22, 2011
Grant date	Jun 18, 2013
Priority date	—
Expiry date	Aug 22, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/144444
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.