Process for preparing 2,2-difluoroethylamine derivatives by alkylation with 2,2-difluoroethyl-1-haloethanes
US8466293B2 · kind B2 · utility
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Key dates
| Filing date | Jun 13, 2011 |
| Grant date | Jun 18, 2013 |
| Priority date | — |
| Expiry date | Sep 28, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/61
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for preparing 2,2-difluorethylamine derivatives of the general formula (III)in which A is an optionally substituted heterocycle as described in the description, by reacting a 2,2-difluoroethyl-1-haloethane compound of the general formula (I)in which Hal is Cl, Br or iodine, with an amine of the general formula (II)in which A is as defined above, optionally in the presence of a base.
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