Patent · US Active

Process for preparing 2,2-difluoroethylamine derivatives by alkylation with 2,2-difluoroethyl-1-haloethanes

US8466293B2 · kind B2 · utility

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20Claims
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Key dates

Filing dateJun 13, 2011
Grant dateJun 18, 2013
Priority date
Expiry dateSep 28, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D213/61
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Process for preparing 2,2-difluorethylamine derivatives of the general formula (III)in which A is an optionally substituted heterocycle as described in the description, by reacting a 2,2-difluoroethyl-1-haloethane compound of the general formula (I)in which Hal is Cl, Br or iodine, with an amine of the general formula (II)in which A is as defined above, optionally in the presence of a base.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.