Processes for the production of hydrogenated products

US8466300B2 · kind B2 · utility

Assignee

• BIOAMBER International S.A.R.L. · LU

Inventors

• Olan S. Fruchey · Port Aransas, US
• Leo Ernest Manzer · Wilmington, US
• Dilum Dunuwila · Okemos, US
• Brian T. Keen · Charleston, US
• Brooke A. Albin · Charleston, US
• Nye A. Clinton · Hurricane, US
• Bernard D. Dombek · Charleston, US

Key dates

• Filing date: Mar 18, 2011
• Grant date: Jun 18, 2013
• Expiry date: May 9, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/32
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for making a hydrogenated product includes providing a clarified DAS-containing fermentation broth; distilling the broth under super atmospheric pressure at a temperature of >100° C. to about 300° C. to form an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt % water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; recovering the solid portion; hydrogenating the solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product including at least one of THF, GBL or BDO; and recovering the hydrogenated product.