Patent · US Active

Method and system for validation of mass spectrometer machine performance

US8467988B1 · kind B1 · utility

9Cited by
4References
20Claims
0Family size

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Key dates

Filing dateJan 2, 2013
Grant dateJun 18, 2013
Priority date
Expiry dateJan 2, 2033

Classification

  • Technology area (CPC H)Electricity
  • CPC primaryH01J49/004
  • WIPO fieldElectrical machinery, apparatus, energy
  • WIPO sectorElectrical engineering

Abstract

A method and system for validating machine performance of a mass spectrometer makes use of a machine qualification set of samples. The mass spectrometer operates on the machine qualification set of samples and obtains a set of performance evaluation mass spectra. The performance evaluation spectra are classified with respect to a classification reference set of spectra with the aid of a programmed computer executing a classification algorithm. The classification algorithm also operates on a set of spectra obtained in a previous standard machine run of the machine qualification set of samples. The results from the classification algorithm are then compared with respect to predefined, objective performance criteria (e.g., class label concordance and others) and a machine validation result, e.g., PASS or FAIL, is generated from the comparison.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.