Inhibition of angiogenesis
US8470607B2 · kind B2 · utility
13Cited by
0References
2Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 17, 2008 |
| Grant date | Jun 25, 2013 |
| Priority date | — |
| Expiry date | Apr 5, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/7014
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to novel methods of inhibiting angiogenesis using chlorotoxin agents. In some embodiments, the inventive methods include intravenous, intraocular, intravitreal, subjunctival injection, and/or topical administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment and/or amelioration of ocular diseases characterized by neovascularization, such as wet macular degeneration. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.