Folate mimetics and folate-receptor binding conjugates thereof
US8470822B2 · kind B2 · utility
15Cited by
67References
8Claims
0Family size
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Key dates
| Filing date | May 7, 2010 |
| Grant date | Jun 25, 2013 |
| Priority date | — |
| Expiry date | Aug 8, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/0497
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This present disclosure relates to folate mimetics and their use in therapeutic and diagnostic applications. More particularly, the disclosure relates to using des-glutamyl folic acid analogs recognized by and selectively bound by folate receptors and other folate binding proteins and the use of such analogs for targeted delivery of diagnostic or therapeutic agents to folate-receptor bearing cell populations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.