Phenyl-sulfamates as aromatase inhibitors

US8470860B2 · kind B2 · utility

Assignee

• Sterix Limited · GB

Inventors

• Lok Wai Lawrence Woo · Slough, GB
• Toby Jackson · Slough, GB
• Christian Bubert · Slough, GB
• Atul Purohit · Slough, GB
• Michael John Reed · London, GB
• Barry Victor Lloyd Potter · Slough, GB

Key dates

• Filing date: Jul 22, 2010
• Grant date: Jun 25, 2013
• Expiry date: Jul 22, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is provided a compound of Formula Iwherein X, Y and Z are each independently of each other an optional linker group; R1 is a ring system; R2 is selected from hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2) and halogens; R3 and R4 are independently selected from H and hydrocarbyl, ring A and B are independently optionally further substituted.