Patent · US Active

Hydroxyalkyl starch derivatives

US8475765B2 · kind B2 · utility

3Cited by

85References

35Claims

0Family size

Assignee

Fresenius Kabi Deutschland GmbH · DE

Inventors

Norbert Zander · Marburg, DE
Harald Conradt · Braunschweig, DE
Wolfram Eichner · Rockenberg, DE

Key dates

Filing date	Aug 12, 2010
Grant date	Jul 2, 2013
Priority date	—
Expiry date	Jan 30, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a method of producing a hydroxyalkyl starch derivative comprising reacting hydroxyalkyl starch of formula (I) at its reducing end which is not oxidized prior to said reaction, with a compound of formula (II) R′NH—R″ (II) wherein R1-R2 and R3 are independently hydrogen or a linear or branched hydroxyalkyl group, and wherein either R′ or R″ or R′ and R″ comprise at least one functional group X capable of being reacted with at least one other compound prior to or after the reaction of (I) and (II), as well as to the hydroxyalkyl starch derivative as such, obtainable by said method, and to a pharmaceutical composition comprising said hydroxyalkyl starch derivative.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.