Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein
US8475798B2 · kind B2 · utility
19Cited by
13References
17Claims
0Family size
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Key dates
| Filing date | Jun 16, 2006 |
| Grant date | Jul 2, 2013 |
| Priority date | — |
| Expiry date | Jul 12, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus epidermidis. The monoclonal antibodies of the invention are advantageous in that they can also recognize binding domains and subdomains of the S. epidermidis SdrF protein in addition to the protein itself. Suitable compositions and passive vaccines based on the monoclonal antibodies of the invention, as well as methods for their use, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.