Meganuclease recombination system
US8476072B2 · kind B2 · utility
6Cited by
0References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 23, 2009 |
| Grant date | Jul 2, 2013 |
| Priority date | — |
| Expiry date | Oct 23, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/902
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a set of genetic constructs which allow the efficient and reproducible introduction of a specific nucleotide sequence at a fixed position in the genome by generating a double strand break at a specific position in the genome using a meganuclease and so stimulating a homologous recombination event at this locus between the genomic site and a transfected donor sequence. The present invention also relates to methods using these constructs and to these materials in the form of a kit.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.