Urine and serum biomarkers associated with diabetic nephropathy
US8476077B2 · kind B2 · utility
3Cited by
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16Claims
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Key dates
| Filing date | Dec 15, 2010 |
| Grant date | Jul 2, 2013 |
| Priority date | — |
| Expiry date | Dec 15, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.