Patent · US Active

Purine-core inhibitors of HSP90 and their use in treating cancer

US8476285B2 · kind B2 · utility

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1References
19Claims
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Assignee

Inventors

Key dates

Filing dateJun 30, 2009
Grant dateJul 2, 2013
Priority date
Expiry dateDec 20, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/34
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to compounds of Formulae I-III:and therapeutic uses thereof, wherein A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group; B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group; R1 is chosen from hydro, alkyl, aryl, heteroaryl, amino, or halo; and L1, L2, are as defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.