Patent · US Active

Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

US8476411B2 · kind B2 · utility

25Cited by
3References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 7, 2011
Grant dateJul 2, 2013
Priority date
Expiry dateJul 7, 2031

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides, are disclosed. The non-natural amino acids, by themselves or as a part of a polypeptide, can include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Methods for making, modifying, and purifying the non-natural amino acid polypeptides are also disclosed. Further, methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses, are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.