Modified-release particles of polyelectrolytes and pharmaceutical formulations thereof
US8481019B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 5, 2008 |
| Grant date | Jul 9, 2013 |
| Priority date | — |
| Expiry date | May 23, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1641
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel particles comprising polyelectrolyte polymers which are transporters of active principle (AP), in particular protein and peptide active principle, and to novel modified-release pharmaceutical formulations comprising said AP microparticles.These novel particles loaded with AP release the AP over a prolonged period of time of several days, or even several weeks.The invention relates, in a first aspect, to particles comprising: The invention also relates to the process for the preparation of these particles, to a pharmaceutical formulation comprising such particles and to a process for the preparation of medicaments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.