Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents
US8481042B2 · kind B2 · utility
14Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2012 |
| Grant date | Jul 9, 2013 |
| Priority date | — |
| Expiry date | Feb 24, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to pyrrolo[1,4]benzodiazepine (PBD) dimer conjugates, to the compositions comprising them and to their therapeutic application, in particular as anticancer agents. The invention also relates to the process for the preparation of the conjugates, to their application as anticancer agents and to the dimers themselves.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.