Patent · US Active

Lisofylline analogs and methods for use

US8481580B2 · kind B2 · utility

0Cited by

10References

7Claims

0Family size

Assignee

University of Virginia Patent Foundation · US

Inventors

Timothy L. Macdonald · Charlottesville, US
Jerry L. Nadler · Charlottesville, US
Peng Cui · Suwon-si, KR

Key dates

Filing date	Feb 25, 2008
Grant date	Jul 9, 2013
Priority date	—
Expiry date	Feb 11, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides analogs of a Lysofylline (LSF), and synthetic methods for the preparation of such analogs. The have the active side chain moiety (5-R-hydroxyhexyl) of LSF and can have greater potency and oral bioavailability than LSF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.