Methods of inhibiting unwanted cell proliferation using an antibody that binds to sonic hedgehog and inhibits hedgehog signaling
US8486400B2 · kind B2 · utility
3Cited by
30References
50Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 1, 2010 |
| Grant date | Jul 16, 2013 |
| Priority date | — |
| Expiry date | Nov 29, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application is directed to compositions and methods for inhibiting angiogenesis and treating or preventing unwanted cell proliferation, including tumors, by inhibiting the hedgehog pathway, e.g., with an antagonist of the hedgehog pathway such as those disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.