Patent · US Active

Nanobubbles useful as an ultrasonic contrast agent for the lymphatic system

US8486444B2 · kind B2 · utility

0Cited by

40References

26Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Thomas B. Ottoboni · Belmont, US
Robert E. Short · Los Gatos, US
Jeffrey D. Gabe · San Bruno, US

Key dates

Filing date	Aug 15, 2011
Grant date	Jul 16, 2013
Priority date	—
Expiry date	Aug 15, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K49/223
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A composition is provided accompanying nanoparticles having diameters in the range of about 100 to 800 nanometers with hollow cores and outer shells with mechanical properties such that they rupture on exposure to predetermined ultrasound energy. The composition is useful for identifying sentinel lymph nodes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.