Beta-glucosidase enzymes
US8486683B2 · kind B2 · utility
4Cited by
6References
15Claims
0Family size
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Key dates
| Filing date | May 28, 2010 |
| Grant date | Jul 16, 2013 |
| Priority date | — |
| Expiry date | Jan 20, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are modified beta-glucosidase enzymes, derived from the Trichoderma reesei Cel3A beta-glucosidase, that exhibit improvements in one or more kinetic parameters (KG, KG2, kcat) comprising amino acid substitutions at one or more of positions 43, 101, 260 and 543. Also provided are genetic constructs comprising nucleotide sequences encoding for modified beta-glucosidase enzymes, methods for the production of modified beta-glucosidase enzymes from host strains and the use of the modified beta-glucosidase enzymes in the hydrolysis of cellulose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.