Lipid tripeptide-based hydrogelator and hydrogel
US8486896B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 4, 2008 |
| Grant date | Jul 16, 2013 |
| Priority date | — |
| Expiry date | Oct 17, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09K23/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided a hydrogelator that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A hydrogelator comprising a lipid peptide represented by Formula (1):(where R1 represents an aliphatic group having 9 to 21 carbon atoms;R2, R3 and R4 independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atom(s) which may have a branched chain having 1 or 2 carbon atom(s), a phenylmethyl group or a —(CH2)n—X group, and at least one of R2, R3 and R4 represents a —(CH2)n—X group; n represents the number of 1 to 4; X represents an amino group, a guanidino group, a —CONH2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which may have 1 to 3 nitrogen atom(s)) or a salt thereof, and a hydrogel comprising the hydrogelator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.