Patent · US Active

Sodium channel blocking compounds tetrodotoxin galactopyranosides

US8486901B2 · kind B2 · utility

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1References

17Claims

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Assignee

WEX MEDICAL LIMITED · CN

Inventor

Weiyang Lin · Kwai Chung, CN

Key dates

Filing date	Mar 26, 2010
Grant date	Jul 16, 2013
Priority date	—
Expiry date	Apr 7, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P29/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel sodium channel blocking compounds tetrodotoxm galactopyranosides of formula I were isolated and purified by HPLC and identified further through IR, NMR, GC, and MS. The compounds have a galactopyranosyl moiety attached to C11 of tetrodotoxin and retain the analgesic activity of the latter. Pharmaceutical compositions and medical uses thereof are further disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.