SnoRNAi-small nucleolar RNA degradation by RNA interference in trypanosomatids
US8486910B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Mar 12, 2012 |
| Grant date | Jul 16, 2013 |
| Priority date | — |
| Expiry date | Mar 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Polynucleotides and a method suitable for downregulation of small nuclear RNA which can be used to treat diseases associated with activity of small nuclear RNA are provided. Specifically, the present invention can be used to downregulate snoRNA molecules or box H/ACA-containing RNA molecules which are involved in diseases such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.