Compounds

US8486968B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Henning Priepke · Warthausen, DE
• Henri Doods · Warthausen, DE
• Raimund Kuelzer · Mittelbiberach, DE
• Roland Pfau · Biberach, DE
• Dirk Stenkamp · Biberach, DE
• Benjamin Pelcman · Stockholm, SE
• Robert Roenn · Uppsala, SE
• Dimitrijs Lubriks · Rīga, LV
• Edgars Suna · Rīga, LV

Key dates

• Filing date: Dec 8, 2011
• Grant date: Jul 16, 2013
• Expiry date: Jan 16, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to compounds of formula Itheir use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, L, M, W, R1, R2, R3, R4, R6, R7, Ra, Rb have meanings given in the description.