Patent · US Active

System and method of automatic estimation of arterial input function for evaluation of blood flow

US8488861B2 · kind B2 · utility

0Cited by

2References

20Claims

0Family size

Assignee

Siemens Aktiengesellschaft · DE

Inventors

Yu Deuerling-Zheng · Erlangen, DE
Jan Boese · Eckental, DE
Michael Zellerhoff · Forchheim, DE

Key dates

Filing date	Oct 3, 2008
Grant date	Jul 16, 2013
Priority date	—
Expiry date	Oct 25, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61B5/055
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

A system and method of determining hemodynamic parameters of a patient is described. A background image data set is obtained prior to the administration of a contrast agent. A series of image data sets is obtained during the first passage of the bolus through a parenchymal volume. The pre-contrast-agent image is subtracted from image data sets obtained during the first passage of the contrast agent bolus, so that the amount of contrast agent in the volume may be determined. The time series of the amount of contrast agent is computed to determine the arterial input function (AIF) which may be used to determine a tissue impulse response, and hemodynamic parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.