Composite particle, contrast agent for photoacoustic imaging, and method for producing the composite particle
US8491908B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 25, 2011 |
| Grant date | Jul 23, 2013 |
| Priority date | — |
| Expiry date | Jun 14, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/533
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a composite particle having a high molar absorption coefficient for detection with higher detection sensitivity in photoacoustic imaging. In the present invention, a composite particle having a particle, a single-chain antibody which includes an antigen recognition region and a region other than the antigen recognition region and which is conjugated with the particle, and an organic dye conjugated with the single-chain antibody, in which the region other than the antigen recognition region of the single-chain antibody has thiol group, and a functional group of the particle is bound to the thiol group, is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.