Targeted therapeutic proteins
US8492338B2 · kind B2 · utility
5Cited by
69References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 25, 2012 |
| Grant date | Jul 23, 2013 |
| Priority date | — |
| Expiry date | May 25, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/924
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.