Aminothiazole compounds as kinase inhibitors and methods of using the same
US8492545B2 · kind B2 · utility
1Cited by
2References
2Claims
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Key dates
| Filing date | Mar 8, 2012 |
| Grant date | Jul 23, 2013 |
| Priority date | — |
| Expiry date | Mar 8, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula I:which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.