Substituted indole compounds

US8492559B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Stefan Schunk · Aachen, DE
• Melanie Reich · Aachen, DE
• Michael Engels · Turnhout, BE
• Tieno Germann · Aachen, DE
• Ruth Jostock · Stolberg, DE
• Sabine Hees · Aachen, DE

Key dates

• Filing date: Feb 3, 2010
• Grant date: Jul 23, 2013
• Expiry date: Mar 11, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted indole compounds corresponding to the formula I:In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).