Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders

US8496957B2 · kind B2 · utility

Assignees

• OTONOMY, INC. · US
• The Regents of the University of California · US

Inventors

• Jay Lichter · Rancho Santa Fe, US
• Benedikt Vollrath · San Diego, US
• Sergio G. Duron · San Diego, US
• Carl Lebel · Malibu, US
• Fabrice Piu · San Diego, US
• Qiang Ye · San Diego, US
• Luis A. Dellamary · San Marcos, US
• Andrew M. Trammel · Olathe, US
• Michael Christopher Scaife · Pittsburgh, US
• Jeffrey P. Harris · Village of La Jolla, US

Key dates

• Filing date: Jul 16, 2009
• Grant date: Jul 30, 2013
• Expiry date: Apr 29, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods for the treatment of otic diseases or conditions with intratympanic compositions and formulations of multiparticulate auris sensory cell modulating agent administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).