Therapy of autoimmune colitis using a TIP60 inhibitor

US8497285B2 · kind B2 · utility

Assignees

• The Trustees of the University of Pennsylvania · US
• THE CHILDREN'S HOSPITAL OF PHILADELPHIA · US

Inventors

• Mark I. Greene · Levittown, US
• Wayne W. Hancock · Philadelphia, US
• Makoto Katsumata · Susono, JP
• Yan Xiao · Suzhou, CN

Key dates

• Filing date: Dec 2, 2011
• Grant date: Jul 30, 2013
• Expiry date: Dec 22, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention is in the fields of immunology and autoimmunity. More particularly it concerns methods of treating patients with compounds which are useful agents for inhibiting the functions of TIP60 in the treatment of an individual suffering, for example, from ulcerative colitis and other irritable bowel diseases.