Patent · US Active

Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production

US8497369B2 · kind B2 · utility

5Cited by

58References

10Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Frank Himmelsbach · Mittelbiberach, DE
Birgit Jung · Laupheim, DE
Ralf Lotz · Schemmerhofen, DE

Key dates

Filing date	Feb 5, 2009
Grant date	Jul 30, 2013
Priority date	—
Expiry date	Jan 2, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to spirocyclic heterocycles of general formula (I)the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways, and the preparation thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.