Optical determination of pH and glucose
US8498682B2 · kind B2 · utility
16Cited by
90References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 2, 2010 |
| Grant date | Jul 30, 2013 |
| Priority date | — |
| Expiry date | Sep 23, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.