Humanized anti-Venezuelan equine encephalitis virus recombinant antibodies
US8501157B2 · kind B2 · utility
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Key dates
| Filing date | Nov 3, 2008 |
| Grant date | Aug 6, 2013 |
| Priority date | — |
| Expiry date | Jun 24, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A CDR grafted humanized recombinant antibody against infection from Venezuelan equine encephalitis virus (VEEV) comprises a human Ig framework having CDRs from murine mAb 1A4A1 VH and VL. DNA sequences, expression vectors incorporating such sequences and transformed host cells are also provided. Also provided are pharmaceutical compositions and methods of prophylaxis and treatment against VEEV infection using the humanized recombinant antibodies of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.