Method of assessing cancer status in a breast cancer patient
US8501483B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 14, 2009 |
| Grant date | Aug 6, 2013 |
| Priority date | — |
| Expiry date | Apr 14, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/54
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described are methods for assessing recurrence status in a breast cancer patient that include assaying a biological sample from the patient for a level of a biomarker selected from such as S100β or HOX-C1I, where positive detection of one or both of the biomarkers indicates a positive recurrence status. The method can be used for prognosis of poor disease free survival in a breast cancer patient, where positive detection of one or both of the biomarkers indicates poor disease survival. The method may also be used for diagnosis of recurrence, where positive detection of circulating S100β is a diagnostic variable of recurrence. The method of diagnosis is carried out on a patient who is undergoing first line therapy and/or a patient who has had surgery to remove a primary breast tumour.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.