Immunoglobulin cleavage fragments as disease indicators and compositions for detecting and binding such
US8501907B2 · kind B2 · utility
8Cited by
3References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 2010 |
| Grant date | Aug 6, 2013 |
| Priority date | — |
| Expiry date | Feb 11, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/734
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.