System and method for estimating cardiac pressure based on cardiac electrical conduction delays using an implantable medical device

US8504152B2 · kind B2 · utility

Assignee

• PACESETTER, INC. · US

Inventors

• Brian Jeffrey Wenzel · San Jose, US
• Dan E. Gutfinger · Craydon Court, US
• Mihir Naware · Redwood City, US
• Xiaoyi Min · Thousand Oaks, US
• Jeffery Siou · San Jose, US
• Anders Bjorling · Järfälla, SE
• Dorin Panescu · Sunnyvale, US

Key dates

• Filing date: Jul 18, 2007
• Grant date: Aug 6, 2013
• Expiry date: Aug 24, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/37258
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom.