Hydrolysis-resistant polyacrylamide gels

US8506781B2 · kind B2 · utility

Assignee

• Bio-Rad Laboratories, Inc. · US

Inventors

• Craig Rowell · Albany, US
• Cory Panattoni · Winters, US
• Tom Berkelman · Oakland, US
• Sean Cater · Oakland, US
• Shane Petersen · Oakland, US
• Lee Olech · Pinole, US
• Xuemei Yang · Alamo, US

Key dates

• Filing date: Jul 23, 2012
• Grant date: Aug 13, 2013
• Expiry date: Jul 23, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08F220/56
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Polyacrylamide gels that offer high resolution in protein separations and are more stable relative to hydrolysis than conventional polyacrylamide gels that rely on Tris or Tris-Bis as buffering agents are made by incorporating triethanolamine in place of most or all of the Tris or Tris-Bis.