Patent · US Active

Treatment of diseases

US8507496B2 · kind B2 · utility

27Cited by
95References
3Claims
0Family size

Assignee

Inventor

Key dates

Filing dateSep 7, 2011
Grant dateAug 13, 2013
Priority date
Expiry dateSep 7, 2031

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides (i) a method of treating metabolic syndrome in an animal, (ii) a method of suppressing the appetite of an animal, (iii) a method of treating obesity in an animal, (iv) a method of reducing the weight of an animal in need thereof, (v) a method of reducing a blood lipid level in an animal in need thereof, (vi) a method of treating non-alcoholic steatohepatitis in an animal, and (vii) a method of inhibiting adipogenesis. The methods comprise administering an effective amount of an active ingredient, wherein the active ingredient comprises a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them to the animal. The invention also provides a kit comprising a container holding a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them; and instructions for administration. The diketopiperazines have the formula given in the application.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.