Patent · US Active

Method for producing β-aminocarbonyl compound

US8507715B2 · kind B2 · utility

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5Claims

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Assignee

National University Corporation Nagoya University · JP

Inventors

Kazuaki Ishihara · Konan, JP
Manabu Hatano · Nagoya, JP
Takahiro Horibe · Nagoya, JP

Key dates

Filing date	Jun 22, 2011
Grant date	Aug 13, 2013
Priority date	—
Expiry date	Jun 22, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D333/24
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

An optically active β-aminocarbonyl compound is obtained by a Mannich reaction between an aldimine in which: nitrogen is protected and a malonic acid diester, in the presence of optically active BINOL and dialkyl magnesium (in which two alkyl groups are the same or different) in an amount 1 to 2 molar times the amount of the BINOL.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.