Method for the production of a single heavy chain antibody
US8507748B2 · kind B2 · utility
9Cited by
4References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 6, 2010 |
| Grant date | Aug 13, 2013 |
| Priority date | — |
| Expiry date | Jul 6, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the generation of single chain immunoglobulins in a mammal. In particular, the present invention relates to a method for the generation of single chain camelid VHH antibodies in a mammal which undergo the process of class-switching and affinity maturation found within antibody producing B cells. Single chain antibodies generated using the method of the present invention and the uses thereof are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.