Surface plasmon resonance sensing method and sensing system

US8508744B2 · kind B2 · utility

Assignees

• THE EUROPEAN UNION, REPRESENTED BY THE EUROPEAN COMMISSION · BE
• University of Pavia · IT

Inventors

• Andrea Valsesia · Borgomanero, IT
• Pascal Colpo · Borgomanero, IT
• François Rossi · Varese, IT
• Franco Marabelli · Pavia, IT

Key dates

• Filing date: Jun 18, 2010
• Grant date: Aug 13, 2013
• Expiry date: Jun 18, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/554
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A SPR sensing method comprising the steps of: providing a SPR sensor comprising a SPR supporting sensor surface and contacting a sample to be analysed with the sensor surface. At least one resonance condition at said SPR supporting sensor surface is monitored by illuminating the sensor surface with an SPR exciting test light beam and sensing the reflected or transmitted test light beam. Additionally, the sensor surface is illuminated with a reference light beam under conditions selected so as not to excite SPR at said sensor surface and sensing the intensity of the reflected or transmitted reference light beam. At least one property of the reflected or transmitted test light beam is determined taking into account the sensed intensity of the reflected or transmitted reference light beam.