Optimized method for LID biosensor resonance detection
US8510082B2 · kind B2 · utility
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7References
28Claims
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Key dates
| Filing date | Jun 2, 2011 |
| Grant date | Aug 13, 2013 |
| Priority date | — |
| Expiry date | Jun 2, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/7743
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.
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