Method of preventing fat graft resorption by administering fat-derived cells and poloxamer P 188
US8512695B2 · kind B2 · utility
21Cited by
39References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 21, 2009 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | Dec 13, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5088
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides polymers for use in preventing damage to the membranes of cells in fat grafts. Mixing of a triblock copolymer such as poloxymer P188 with adipocytes or adipose tissue to be transplanted into a subject is thought to stabilize the membranes of the cells leading to more successful fat transplantation in soft tissue reconstruction or augmentation. Such methods may also be used in the transplantation of adult stem cells or other cells derived from fat tissue. Other agents such as lipoic acid may also be added to the polymer/cell compositions for cell transplantation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.