Patent · US Active

Protein (poly)peptides libraries

US8513164B2 · kind B2 · utility

0Cited by

28References

8Claims

0Family size

Assignee

MORPHOSYS AG · DE

Inventors

Achim Knappik · Gräfelfing, DE
Peter Pack · Unterföhring, DE
Liming Ge · Munich, DE
Simon Moroney · Hersbruck, DE
Andreas Plückthun · Zürich, CH

Key dates

Filing date	Dec 21, 2006
Grant date	Aug 20, 2013
Priority date	—
Expiry date	Dec 21, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a method of identifying one or more genes encoding one or more proteins having an optimized property. In particular, the method comprises expressing a collection of genes and screening for a desired property, identifying a plurality of genes having the desired property, and replacing one or more one or more sub-sequences of each of said genes with a different, compatible genetic sub-sequence, and screening again in order to identify genes encoding proteins having an optimized property.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.