Crosslinked PEI nanoparticle transfection agents for delivery of biomolecules with increased efficiency
US8513206B2 · kind B2 · utility
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4References
12Claims
0Family size
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Key dates
| Filing date | Jul 29, 2008 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | Oct 24, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel crosslinked polyethylenimine (PEI) nanoparticle based nucleic acid transfection agent wherein the crosslinker is having carbon chain in the range of C2 to C8, ranging between 3.27-19.8%, having the size of nanoparticle ranging between 20-600 nm and zeta potential ranging from +5 to 50 mV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.