Cytochrome P450 inhibitors and uses thereof

US8513291B2 · kind B2 · utility

Assignee

• Angion Biomedica Corp. · US

Inventors

• Bijoy Panicker · Holbrook, US
• Lambertus J.W.M. Oehlen · Westbury, US
• James G. Tarrant · Hamden, US
• Dong Sung Lim · Fair Lawn, US
• Xiaokang Zhu · Great Neck, US
• Dawoon Jung · Tenafly, US
• Rama K. Mishra · Chicago, US

Key dates

• Filing date: Jun 1, 2011
• Grant date: Aug 20, 2013
• Expiry date: Jun 1, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.