Methods and compositions for detecting amyotrophic lateral sclerosis
US8513387B2 · kind B2 · utility
6Cited by
15References
21Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 21, 2010 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | Mar 2, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides binding proteins that bind to misfolded or monomeric SOD1, and not to native homodimeric SOD1. The invention also includes methods of diagnosing, detecting or monitoring amyotrophic lateral sclerosis in a subject. In addition, the invention provides methods of identifying substances for the treatment or prevention of amyotrophic lateral sclerosis and kits using the binding proteins of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.