Tetrahydro-imidazo[1,5-α] pyrazine derivatives, preparation process and medicinal use thereof

US8513411B2 · kind B2 · utility

Assignee

• JIANGSU HENGRUI MEDICINE CO., LTD. · CN

Inventors

• Peng Cho Tang · Moraga, US
• Fanglong Yang · Shanghai, CN
• Jiang Fan · Hubei, CN
• Hu Feng · Zhengzhou, CN
• Yang Wang · Kingston, CA
• Tao Yang · Taizhou City, CN

Key dates

• Filing date: May 3, 2012
• Grant date: Aug 20, 2013
• Expiry date: May 3, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof as medicaments, especially as dipeptidyl peptidase IV inhibitors, wherein the substituents of formula (I) are defined as same as the description.