Compositions and methods comprising analogues of radicicol A
US8513440B2 · kind B2 · utility
3Cited by
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16Claims
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Key dates
| Filing date | Jun 5, 2008 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | Jun 6, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D327/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are novel analogues of the natural product radicicol A of formulae I, .Ia, pi, Ha, lib and HI, pharmaceutical compositions comprising the compounds. The compounds of the invention are kinase and phosphatase inhibitors and find utility in the treatment or prevention of kinase and phosphatase-mediated disorders. Also provided are uses and methods for the treatment or prevention of kinase- and phosphatase-mediated disorders and synthetic processes for the preparation of the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.